immunofluorescence

Mesangial Deposits
June 17, 2020

Electron microscopy of a biopsy specimen in a patient with IgA nephropathy. Electron dense deposits can be identified in the mesangium (black arrows), which on immunofluorescence would have predominant or co-dominant IgA staining. Note that although mesangial IgA deposits are classic in IgA nephropathy and IgA vasculitis (former Henoch-Schonlein purpura…

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Segmental glomerulosclerosis in IgA nephropathy
June 16, 2020

A patient with IgA nephropathy and associated segmental glomerulosclerosis. Images courtesy of Patrick Walker, MD.

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Immunofluorescent staining in C3 glomerulopathy
June 5, 2020

Immunofluorescent staining pattern in a patient with C3 glomerulopathy. There is strong C3 staining in the capillary loops and mesangium. Immunoglobulin staining, such as IgG, is typically absent or at a lower intensity by at least two orders of magnitude than C3.  Images courtesy of Patrick Walker, MD.

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ASPN Summer 2024 Virtual Town Hall Meeting
June 28 @ 12:30 pm - 1:30 pm EDT
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