Immunofluorescent staining in C3 glomerulopathy

Immunofluorescent staining pattern in a patient with C3 glomerulopathy. There is strong C3 staining in the capillary loops and mesangium. Immunoglobulin staining, such as IgG, is typically absent or at a lower intensity by at least two orders of magnitude than C3.  Images courtesy of Patrick Walker, MD.