Perihilar FSGS
June 16, 2020

Perihilar variant of focal segmental glomerulosclerosis (FSGS). Hyaline deposition and sclerosis occur at the vascular pole of the glomerulus. This variant is believed to be a secondary form of FSGS, occurring as an adaptive response to other injuries resulting in loss of functioning nephrons, such as in obesity-related kidney disease.…

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Focal segmental glomerulosclerosis
February 13, 2020

Focal segmental glomerulosclerosis (FSGS) in a child presenting with nephrotic syndrome. Image courtesy of Joseph Gaut, MD PhD.

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Focal and segmental glomerulosclerosis
September 27, 2019

Segmental obliteration of the glomerular capillary lumen in a patient with FSGS. Note the sclerotic portion of the glomerular tuft is adherent to Bowman’s capsule. There is proximal tubular hypertrophy, which can be seen in this condition in response to heavy proteinuria. Image courtesy of Brian Stotter, MD.

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