IgA nephropathy with crescents. Note the fibrocellular crescent present in this glomerulus extending from the 3 o’clock the 12 o’clock position. Though difficult to appreciate in this image, there is mild mesangial hypercellularity. Image courtesy of Joseph Gaut, MD PhD.
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ASPN Strategic Plan 2022-2027 Mission: The ASPN is the leading voice of pediatric nephrology in North America. Our primary goal is to advance care for children, adolescents, and young adults with kidney disease through advocacy, education, research, and workforce development. Goal 1: Ensure a diverse, sustainable, and robust pediatric nephrology…
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PAS stain of a glomerulus in a patient with SLE nephritis. There is endocapillary and mesangial proliferation, as evidenced by thickened, occlusive capillary loops and increased mesangial cellularity. Note the “wire loop” lesions (arrows) and hyaline thrombi present (arrowheads). Image courtesy of Joseph Gaut, MD, PhD.
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Tubuloreticular inclusions in a patient with diffuse proliferative SLE nephritis (SLE class IV). These subcellular structures (dark circular clusters) on transmission electron microscopy are localized to the cytoplasm of endothelial cells, and thought to be formed in high interferon states. These are classic for SLE nephritis, but can be seen…
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CT scan axial view with contrast showing right kidney upper pole defects, consistent with acute pyelonephritis
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Segmental obliteration of the glomerular capillary lumen in a patient with FSGS. Note the sclerotic portion of the glomerular tuft is adherent to Bowman’s capsule. There is proximal tubular hypertrophy, which can be seen in this condition in response to heavy proteinuria. Image courtesy of Brian Stotter, MD.
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The glomerular capillary bed is thickened, with the presence of double contours reflecting circumferential mesangial expansion into the capillary wall (mesangial interposition). In this biopsy core of chronic allograft injury there is minimal interstitial inflammation, primarily localized to the areas of tubular atrophy, and severe interstitial fibrosis.
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It is with profound sadness that we announce the passing of our colleague and friend, Dr. Eunice John. Dr. John retired as Professor of Pediatrics at the University of Illinois College of Medicine after serving UIC residents and patients for 42 years. Dr. John, who was chief of pediatric…
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In the first of three ASPN 2019 annual meeting podcasts, ASPN President Patrick Brophy, MD speaks with Gina-Marie Barletta, MD, Kim Reidy, MD, Jeffrey Kopp, MD, and Stella Shin, MD. The group discusses the activities taking place during the first day of the Annual Meeting.
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