Archive for 2020
H. William Schnaper Tribute Page
Life Course Journey of a True Mensch H. William (Bill) Schnaper was the Irene Heinz Green & John LaPorte Given Chair in Pediatric Research and Tenured Professor & Vice Chair,…
Read MoreJohn Herrin (2020)
It is with great sadness that we announce the passing on October 25, 2020 of John T. Herrin, MBBS, FRACP, 84, former Director of Clinical Services within the Division of Nephrology at Boston…
Read MoreMesangial Deposits
Electron microscopy of a biopsy specimen in a patient with IgA nephropathy. Electron dense deposits can be identified in the mesangium (black arrows), which on immunofluorescence would have predominant or…
Read MorePerihilar FSGS
Perihilar variant of focal segmental glomerulosclerosis (FSGS). Hyaline deposition and sclerosis occur at the vascular pole of the glomerulus. This variant is believed to be a secondary form of FSGS,…
Read MoreGlomerulomegaly
A normal glomerulus (left) and hypertrophied glomerulus (glomerulomegaly, right). Glomerulomegaly is an adaptive response to decreased nephron number (e.g. prematurity) and/or increased demand (e.g. obesity). Patients with glomerulomegaly may have…
Read MoreSegmental glomerulosclerosis in IgA nephropathy
A patient with IgA nephropathy and associated segmental glomerulosclerosis. Images courtesy of Patrick Walker, MD.
Read MoreRickets
Early radiographic changes on left knee X-ray in an infant with hypophosphatemic rickets. There is decreased mineralization of the long bones and splaying, or widening, at the distal femur and…
Read MoreAcute interstitial nephritis
A mixed inflammatory cell infiltrate in a child with acute interstitial nephritis. Image courtesy of Patrick Walker, MD.
Read MoreWBC casts
WBC casts (black arrows) in a biopsy specimen of a patient with acute interstitial nephritis. Images courtesy of Patrick Walker, MD.
Read MoreAutosomal recessive polycystic kidney disease (ARPKD)
Gross pathology and low-power light microscopy of kidney tissue in a neonate with ARPKD. The kidneys are enlarged but maintain their reniform shape, and are full of microscopic cysts derived…
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